Marco Bezzecchi of VR46 Racing has won the inaugural Indian Grand Prix with a dominant performance from start to finish while Ducati's Francesco Bagnaia suffered a crash that blows the world championship contest wide open.

Pole-sitter Bezzecchi lost out on a sprint podium after a collision with teammate Luca Marini, eventually finishing fifth, but on Sunday there was no rider in the chasing pack who could match the determined Italian's pace up front.

Pramac Racing rider and sprint winner Jorge Martin, who risked a penalty by unzipping his leathers in the heat, finished second while Yamaha's Fabio Quartararo completed the podium after the two were involved in a tense battle on the final lap.

World championship leader Bagnaia seemed to be cruising in second place but lost his balance on turn five with eight laps to go, allowing Martin to move up to second and close the gap to 13 points while Bezzecchi is 44 points behind.

"I'm very happy, it was a tough race, very long. After yesterday, unfortunately I was hit in the start and today I wanted revenge," Bezzecchi said in a pit lane interview.

"I started well. I got on the lead early and then I was focused. I enjoyed this track."

Bagnaia initially took the lead on the straight at the Buddh International Circuit, with Martin braking late and going wide in a desperate but ultimately futile attempt to keep the faster Ducati behind him.

But Bezzecchi also capitalised to move up to second before the pole sitter moved into the lead at the end of the first lap and his searing pace allowed the Italian to extend his lead to more than two seconds after four laps.